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| Ferrous Fumarate C4H2FeO4 Hazardous Substance Databank Number: 7348 |
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| Ferrous fumarate is the anhydrous salt formed by combining ferrous iron with fumaric acid and used as a hematinic (a preparation used to improve the quality of blood). Unfortunately, inorganic iron is pro-oxidative, stimulating the damaging effects in the body of substances known as free radicals..(1) There is evidence linking high inorganic iron intake to cardiovascular disease and cancer. Excessive iron accumulates in the liver, and may feed bacterial and viral infection. Iron is found, in a healthy body, in the form of metalloproteins, because in exposed or in free form it causes production of free radicals that are generally toxic to cells. In its "free" form iron binds avidly to virtually all biomolecules so it will adhere nonspecifically to cell membranes, nucleic acids, proteins etc, causing substantial damage. When, for instance, iron binds with LDL, it oxidizes it, resulting in obstruction. After all, how can something which is the #1 cause of death by poisoning of children under the age of 6, be safe for ingestion, at any dose? |
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| Wikipedia "Iron Precautions" Link |
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