Crospivodone
N-vinyl-2-pyrrolidone
HSDB Number: 205.
A synthetic homopolymer of cross-linked N-vinyl-2-pyrrolidone, Crospivodone, like many forms of
vinyl, are not appropriate for human consumption and have demonstrated mutagenic/carcinogenc
effects. Very little research has been done on the toxicity of this biologically unprecedented
synthetic, however, animal studies showed this substance was carcinogenic, caused inflammation,
pneumonia, and other adverse effects.


Just to give you a sense of how incredibly alien this stuff must be to the body, here is a
description from the Hazardous Substances Data Bank of how it is manufactured:
"Polyvinylpryrrolidone is prepared by Reppe's process: 1,4-butanediol obtained in the Reppe
butadiene synthesis is dehydrogenated over copper at 200 deg C forming gamma-butyrolactone;
reaction with ammonia yields pyrrolidone. Subsequent treatment with acetylene gives the vinyl
pyrrolidone monomer." (The Merck Index, 1996., p. 1320).   Keep in mind that intermediates in the
production of crospovidone like "butadiene" are already known to have deleterious effects.